吴建国

  发布时间: 2018-03-13   信息员:   

  

 

   吴建国,1981年生,博士,教授,博士研究生导师;国家优秀青年基金获得者;教育部霍英东基金获得者;中国植物病理学会-青年植物病理学家奖获得者;福建省五四青年奖章获得者;福建农林大学 “金山学者”拔尖人才。2012年获福建省“优秀博士论文二等奖”。2013年入选福建省高校杰出青年科研人才培育计划;2014年入选福建省青年拔尖人才。2010-2016年于北京大学生命科学学院李毅教授和清华大学生命学院戚益军教授实验室从事博士后研究工作,并荣获北京大学-清华大学生命科学联合中心2011-2016年优秀博士后基金;罗氏优秀博士。参加并主持国家“973”和“863”计划项目子课题的研究;2017年福建省新世纪优秀人计划。主要从事植物病毒的分子生物学以及病毒与寄主互作的相关研究,其研究成果在eLife, Nature Plants, PLoS Pathogens和Molecular Plant等杂志上发表SCI论文18篇,累计影响因子>100,5年内文章累计被引用近400次。担任Annals of Phytopathology编委,中国植物病理学会青年学术委员会副主任。

  

研究兴趣:

1.基于RNA沉默的水稻抗病毒机制;

2.病毒与宿主的相互作用以及病毒对宿主发育的影响;

3.病毒侵染寄主后病害症状的形成机制;

My interesting research:

My research interests major on virus–host interactions and the function of host factors involved in virus-host interaction and plant defense against pathogens. These projects fall into several specific topics: 

1.The mechanism of rice defensing virus based on RNA silencing.

2.The plant-virus interaction and the influence of virus on plant development.

3.Disease symptoms development during the virus infection.

E-mail:wujianguo81@126.com

已发表论文:

(1)Jianguo Wu#, Rongxin Yang#, Zhirui Yang#, Shengze Yao, Shanshan Zhao, Yu Wang, Pingchuan Li, Xianwei Song, Lian Jin, Tong Zhou, Ying Lan, Lianhui Xie, Xueping Zhou, Chengcai Chu, Yijun Qi, Xiaofeng Cao* and Yi Li*.ROS Accumulation and Antiviral Defence Control by MicroRNA528 in Rice.Nature Plants, 2017, 3, 16203.被引用17.

(2)Shanshan Zhao, Wei Hong,Jianguo Wu, Yu Wang, Shaoyi Ji, Shuyi Zhu,Chunhong Wei, Jinsong Zhang, Yi Li*,A viral protein promotes host SAMS1activity and ethylene production for thebenefit of virus infection,eLife, 2017,6:e27529.

(3)Lijia Zheng, Chao Zhang, Chaonan Shi, Yu Wang, Tong Zhou, Feng Sun,Hong Wang, Shanshan Zhao, Qingqing Qin, Rui Qiao, Zuomei Ding, Chunhong Wei, Lianhui Xie*,Jianguo Wu*, Yi Li*,Rice stripe virus NS3 proteinregulates primary miRNA processing throughassociation with the miRNA biogenesis factorOsDRB1 and facilitates virus infection in rice.PLoSPathogens,2017,13(10): e1006662.

(4)Jianguo Wu#, Zhirui Yang#, Yu Wang, Lijia Zheng, Ruiqiang Ye, Yinghua Ji, Shanshan Zhao, Shaoyi Ji, Ruofei Liu, Le Xu, Hong Zheng, Yijun Zhou, Xin Zhang, Xiaofeng Cao, Lianhui Xie, Zujian Wu*, Yijun Qi* and Yi Li*.Viral-InducibleArgonaute18 confers broad-spectrum virus resistance in rice by sequestering a hostmicroRNA.eLife, 2015, 4:e05733.IF: 9.33,被引用71.

(5)Peng Du#,Jianguo Wu#, Jiayao Zhang, Shuqi Zhao, Hong Zheng, Ge Gao, Liping Wei and Yi Li*.Viral infection induces expression of novel phased microRNAs from conserved cellular microRNA precursors.PLoS Pathogens, 2011,7(8):e1002176.IF: 9.187被引用98.

(6)Chao Zhang#, Zuomei Ding#, Kangcheng Wu#, Liang Yang, Yang Li, Zhen Yang, Shan Shi, Xiaojuan Liu, Shanshan Zhao, Zhirui Yang, Yu Wang, Luping Zheng, Juan Wei, Zhenguo Du, Aihong Zhang, Hongqin Miao, Yi Li,Zujian Wu* and Jianguo Wu*. Suppression of Jasmonic Acid-mediated Defense by Viral-inducible MicroRNA319Facilitates Virus Infection in Rice. Molecular Plant, 2016,9: 1372-1384.IF: 7.12被引用3.

(7)Chao Zhang#, Zujian Wu Yi Li andJianguo Wu*.Biogenesis, Function and Applications of Virus-Derived Small RNAs in Plants.Frontiers in Microbiology, 2015, 6:1237.IF: 4.0被引用37.

(8)Zhenguo Du#, Donglai Xiao#, Jianguo Wu#, Dongsheng Jia, Zhengjie Yuan, Ying Liu, Liuyang Hu, Zhao Han, Taiyun Wei, Qiying Lin, Zujian Wu*and Lianhui Xie*.P2 of RSVinteracts with OsSGS3 and is a silencing suppressor.Molecular Plant Pathology, 2011,12(8):808-14. IF: 4.2被引用54.

(9)Jianguo Wu#, Chunzheng Wang, Zhengguo Du, Lijun Cai, Meiqun Hu, Zujian Wu*, Yi Li*and Lianhui Xie*.Identification of Pns12 as the second silencing suppressor ofrice gall dwarf virus.Science China Life Sciences, 2011,54 (3): 201-208.IF: 1.88被引用11.

(10)Jianguo Wu#, Zhenguo Du#, Chunzheng Wang, Lijun Cai, Meiqun Hu, Qiying Lin, Zujian Wu*, Yi Li* and Lianhui Xie*. Identification of Pns6, a putative movement protein of RRSV, as a silencing suppressor.Virology Journal, 2010, 7:335.IF: 2.2被引用22.

(11)Zujian Wu#, JianguoWu#, Scott Adkins, Lianhui Xie* and Weimin Li*.Rice ragged stunt virussegment S6-encoded nonstructural protein Pns6 complements cell-to-cell movement of Tobacco mosaic virus-based chimeric virus, Virus research, 2010,152:176-179. IF:3.08被引用24.

(12)Chao Zhang#, Xiaojuan Liu#, Kangcheng Wu, Luping Zheng, Zuomei Ding, Fei Li, Peng Zou, Liang Yang,Jianguo Wu* and Zujian Wu*.Rice grassy stunt virus nonstructural protein p5 serves as a viral suppressor of RNA silencing and interacts with nonstructural protein p3.Archives of Virology,2015, 160(11): 2769-2779.IF: 2.5被引用1.

(13)Liang Yang#, Zhenguo Du#, Feng Gao, Kangcheng Wu, Lianhui Xie, Yi Li, Zujian Wu* andJianguo Wu*Transcriptome profiling confirmed correlations between symptoms and transcriptional changes in RDV infected rice and revealed nucleolus as a possible target of RDV manipulation.Virology Journal, 2014, 11:81. IF: 2.2.被引用2次。

(14)Lian Jin#, Qingqing Qin, Yu Wang, Yingying Pu, Lifang Liu, Xing Wen, Shaoyi Ji,Jianguo Wu, Chunhong Wei, Biao Ding and Yi Li*.Rice Dwarf Virus P2 Protein Hijacks Auxin Signaling by Directly Targeting the Rice OsIAA10 Protein, Enhancing Viral Infection and Disease Development.PLOS Pathogens.2016, 12(9):e1005847. doi:10.1371/journal.ppat.100584.

(15)Luping Zheng#, Zhenguo Du#, Chen Lin, Qianzhuo Mao,Kangcheng Wu,Jianguo Wu, Taiyun Wei, Zujian Wu* and Lianhui Xie*. Rice Stripe Tenuivirus p2 may Recruit or Manipulate Nucleolar Functions through an Interaction with Fibrillarinto Promote Virus Systemic Movement.Molecular Plant Pathology. 2015,16 (9): 921–930.IF:4.2被引用5.他引3.

(16)Jang-Kyun Seo#,Jianguo Wu, Yifan Lii, Yi Li* and Hailing Jin*.Contribution of small RNA pathway components in plant immunity.Molecular Plant-Microbe Interactions. 2013,26(6):617-25.IF: 4.8被引用56.

(17)Junwei Guo#, Fangli Ren, Yinyin Wang, Shan Li,Zhengrong Gao, Xiaoyan Wang,Hongxiu Ning,Jianguo Wu,Yi Li, Zhao Wang, Shek Man Chim, Jiake Xu and Zhijie Chang*.miR-764-5p promotes osteoblast differentiation through inhibition of CHIP/STUB1 expression.Journal of Bone and Mineral Research. 2012, 27(7):1607–1618 IF: 7.056;被引用27.

(18)Chunzheng Wang#, Feng Gao,Jianguo Wu,Jianli Dai,Chunhong Wei and Yi Li*ArabidopsisDeacetylase AtSRT2 Regulates Disease Resistance by Suppressing PAD4, EDS5, and SID2 Expression.Plant andCell Physiology,2010, 51(8): 1291-1299.IF: 4.978;被引用49.

备注:#表示第一和共同第一作者论文;*表示通讯和共同通讯作者论文